Description

The Core is comprised of three complementary components that provide the following services.

The Genomics Component provides:

• access to genomics, epigenomics, transcriptomics, proteomics, and metabolomics technologies
• facilitation of microbiome analysis
• consultation to ensure that the full potential of the aforementioned technologies is realized
• facilitation of single cell RNA-Seq experiments
• facilitation of spatial transcriptomics profiling experiments
• isolation and QC of nucleic acids
• targeted gene expression analysis
• targeted genotyping
• multiplex immunoassays using the Meso Scale Discovery platforms as well as ELISA
• sample management
• support for the preparation of grant proposals and manuscripts

The Bioinformatics & Biostatistics Component provides:

• experimental design consultation
• comprehensive state-of-the-art statistical and bioinformatics analysis for OMICs data (e.g. genomics, epigenomics, transcriptomics,
• proteomics, metabolomics) as well as non-OMICS data
• assistance with data management and sharing
• support for the preparation of grant proposals and manuscripts

The Microphysiological Systems Component provides:

• consultation and access to 2D and 3D microphysiological system models that utilize human, canine, rodent and other mammalian cells to investigate toxicological responses for candidate xenobiotics
• support for the preparation of grant proposals and manuscripts

Key Words

Experimental Design Consultation, Genomics, Transcriptomics, Epigenomics, Proteomics, Metabolomics, Statistical and Bioinformatics Analysis of Omics Data, Microphysiological Systems, Genotyping, Gene Expression